Made in Japan Beauty Products

To all our customers,

To all our customers, Here at Majestic Beauty made in Japan beauty products, we are committed to providing you with the best Japanese skin care products and services of the highest quality. Our sincere aim is to live up to our customers’ expectations in full and to bring them happiness and good fortune through our products.

With our sincere best wishes,

From Majestic Beauty

Bringing you the “14 Day Miracle”

With the most Japanese cosmetic products, it takes three months or more to see any changes in your skin. Our newly developed beauty serum gives you clear results in just 14 days!

Why 14 days?

The skin’s turnover time (renewal period) is typically 28 days. Cells take 14 days to move up from the skin’s basal layer to the granular layer; they then take another 14 days to form keratinocytes, and finally flake off. New cells are continually formed over this 14 day period, and then pushed up from the basal layer.

  • Old Skin

    Stratum corneum (horny layer)

    Stratum granulosum (granular layer)

    Stratum Spinosum (spinous layer)

    Stratum basale (basal layer)

Majestic Skin made in Japan beauty products encourages natural and healthy skin turnover, ensuring new cells form continuously over the 14-day period.

*The process of skin renewal and regeneration is called skin “turnover”. Cells are formed in the basal layer, and change shape as they move up to the surface. The cells become corneocytes (without nuclei) and die. These cells are pushed to the surface by newer cells. Eventually they naturally redden and flake off.

Benefit of Made in Japan Beauty Products

“Before and after” photos

Long-term acne scars have visibly improved, and skin pores are less prominent.
Skin appearance and acne have improved. Skin elasticity has also improved.
Acne scarring has improved. Skin appears plumper. (Subject in early 40's)

A specially prepared formulation using culture fluid extract from human stem cells

Ultra-high concentration 20%

Ultra-high concentration

Special ingredients are blended to produce a concentration to give you outstanding results.

Up to 150 different growth factors are condensed into our product. Feel its luxurious concentration on your skin.

Liposome technology Reaches deep into the skin

Liposome technology reaches deep into the skin

Our product uses artificial capsules replicating the cell membrances enclosing human cells.

Tiny capsules surrounded by lipids effectively deliver active ingredients deep into the skin.

“Cold process” formulation No heat require

Handling precious ingredients with care

The stem cell culture extract is extremely delicate. Other cosmetics manufactures typically use heat as part of their manufacturing process.

Majestic Skin uses a special formulation that does not require heat, So ingredients are unharmed, and can be effectively absorbed by your skin.

*Active product ingredient: Human stem cell conditioned culture fluid extract

Japanese skin care brands

Stem cell culture fluid extract is a state-of-the-art beauty ingredient which promotes cellular activity and aids the skin’s lifecycle.

Contains protein ingredients secreted when stem cells extracted from human fat are cultured. Subject to rigorous blood and DNA testing before use. Human adipose stem cell culture fluid is reported to contain over 150 growth factor protein ingredients derived from stem cells, including VEGF (Vascular endothelial growth factor), TGF (Transforming growth factor), FGF (Fibroblast growth factor), IGF (Insulin-like growth factor). These promote activity in the epidermal cells which produce skin, and in the fibroblasts which produce collagen, elastin and hyaluronan. They are self-regenerating.

Cells decline with age and metabolism slows down

Growth factors promote regular skin turnover

Skin elasticity, clarity

Old skin turns red and flakes off

Cells divide and move towards the skin’s outer layer

New cells are formed

Declining levels of collagen, elastin and hyaluronan

Encouraging collagen, elastin and hyaluronan

Human stem cell culture fluid extract

  • Human stem cell culture fluid extract
  • FGF
  • Hyaluronan

Growth factors activate cells by connecting with cellular receptors.

  • Fibroblasts promoting cell proliferationHyaluronan promoting cell proliferation Collagen promoting cell proliferation
  • Dealing with the root cause of skin disorders.

Component ingredients used for Majestic Skin (human stem cell culture extract)

Product name: ADSC-CM INCI name: Human Adipocyte Conditioned Media Extract Display name: Human stem cell conditioned culture fluid extract

Effects Of Cosmetic made in japan

1. Tissue regeneration 2. Promotion of collagen, hyaluronan biosynthesis 3. Proliferation of keratinocytes and fibroblasts 4. Skin whitening 5. Hair growth

Human stem cell culture fluid (ADSC-CM)

ADSC-CM is produced through secretion. It is rich in physiologically active substances such as cytokines, enzymes, and ECM constituent proteins. It has a range of uses as an activating ingredient, rejuvenating cells where activity has declined due to aging. ADSCM-CM promotes the biosynthesis of collagen and hyaluronan; smooths skin and protects against wrinkles; whitens the skin; stimulates production of fibroblasts, stem cells and epidermal cells; promotes hair growth; and has a range of anti-aging properties.

What is human stem cell culture fluid (ADSC-CM)?

ADSC-CM is a protein ingredient secreted from cultured adipose stem cells extracted from human fat. Adipose stem cells are a type of fully-grown stem cell. They are easier to extract than bone marrow stem cells or umbilical cord blood cells, and, because of their abundance, have been increasingly used in anti-aging treatments and beauty products. Human adipose stem cell culture fluid is reported to contain over 150 growth factor protein ingredients derived from stem cells, including VEGF (Vascular endothelial growth factor), TGF (Transforming growth factor), FGF (Fibroblast growth factor), IGF (Insulin-like growth factor). ADSCM-CM is highly functional substance that prevents skin aging and damage, and promotes the regeneration of hyaluronan, collagen and elastin which are essential components of skin tissue. Stem cell culture fluid is recognized to have a range of uses, including for anti-aging treatments and the promotion of tissue regeneration.

Stem cell culture fluid

Elastin

Hyaluronan

Collagen

The substances secreted by stem cells are rich in physiologically active ingredients and proteins needed for tissue regeneration. Physiologically active cytokines play a key role in activating cells through combining with cell receptors. Also, extracellular proteins such as hyaluronan, collagen and elastin help the process of tissue formation.

ADSC-CM is absorbed directly by stem cells, fibroblasts and epidermal stem cells. It promotes cell activation and cell reproduction, and accelerates the skin tissue regeneration process.

Hyaluronan Expression Results

Hyaluronan proliferation

The graph in Diagram 1 shows hyaluronan generation by ADSC-CM. The lines on the graph show the amount of fibroblast hyaloronan produced in order, starting with the negative control group from the bottom (untreated test group); then the positive control group (treated with TGF-ß1: growth factor stimulating hyaluronan production); then ADSC-CM over a period of 12/24/36/48 hours. In this test ADSC-CM is observed to induce a larger volume of hyaluronan expression than the positive test control group using a hyaluronan growth factor.

Effectiveness test: Fibroblast proliferation

  • Fibroblast increase

This graph shows the results of the fibroblast proliferation acceleration test. ADSC-CM was applied to fibroblast cells for a 48-hour period, and the cell proliferation rates were placed in order, with the promotion of cell proliferation observed according to concentration

Photographs of fibroblast proliferation test

What are fibroblast anyway?

Fibroblast cells are the source of collagen,elastin and hyaluronan, which are vital for skin tension and elasticity.

When the fibroblast cells are active, collagen, elastin and hyaluronan ensure our skin’s metabolism is working smoothly, and keep our skin firm and supple.

However, when fibroblast cells decline and stop working due to damage from aging or ultraviolet rays, the skin’s metabolism slows down. Declines in collagen and elastin through skin degeneration means the skin loses elasticity, and declines in hyaluronan lead to a reduction in the skin’s moisture levels. As a result, subcutaneous tissue becomes loose.

This Causes skin wrinkles & sagging

Also, fibroblast cells do not divide as readily as cells in the epidermis (for example, in the stratum corneum). This makes treatment of wrinkles and sagging skin difficult.

You need to start looking after the fibroblast cells in your skin as soon as possible.

Three features of fibroblast cells

  • 1 They produce the key components of healthy skin (collagen · elastin · hyaluronan);
  • 2 They help cells to divide, and help fibroblast cell proliferation;
  • 3 They bind collagen to maintain the structural integrity of the dermis.

Essential for skin tension and elasticity

  • Collagen Skin tension

    Elastin Skin

    Hyaluronan Skin

  • Fibroblasts produce these

Key ingredients to keep your skin in top condition

Looking after your skin now and in the future

Hyaluronan: 3 types High molecular mass; Low molecular mass; Low molecular mass; Nano particles Blended with 3 hyaluronan types, keeping the skin fully moisturized

Collagen: 2 types Indispensable for skin elasticity: Low molecular collagen; atelocollagen Blended with 2 collagen types

Yeast extract to repair injured skinBlended with hydrolyzed yeastextract to mend damaged epidermal cells

Instructions for use

  • Cleaning your face

  • sing Majestic Skin

  • Skincare basics

Wash your face and towel it dry. Apply Majestic Skin. * After application , carry on as you would normally.

  • STEP 1

    Place some serum on your fingertips.
  • STEP 2

    Spread the serum over your face.
  • STEP 3

    Gently press and massage the serum into your face using the pads of your fingers.

Recommended method of use. 14 Day Program

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